Maxillary distraction osteogenesis versus orthognathic surgery for cleft patients

Happy baby is smilingCleft lip and palate is one of the most common birth defects and can cause difficulties with feeding, speech and hearing, as well as psychosocial problems. Treatment of clefts is lengthy, typically taking from birth to adulthood to complete. Upper jaw growth in cleft patients is highly variable, and in a relatively high percentage, it does not develop completely. A type of surgery called orthognathic surgery, which involves surgical cutting of bone to realign the upper jaw (osteotomy), is usually performed in this situation. An alternative intervention is known as distraction osteogenesis, which achieves bone lengthening by gradual mechanical distraction (cutting of bone and moving the ends apart incrementally to allow new bone to form in the gap). This review is an update of the original version that was published in 2016. Continue reading

Prioritising our reviews – the results are in!

prioritiesThe Cochrane Oral Health Group has been conducting a prioritisation exercise over the last six months, and the results are now available! Continue reading

Have your say and help us to prioritise…


Photo copyright Erik Christensen under Creative Commons Licence

The Cochrane Oral Health Group has begun the task of prioritising clinically important systematic review titles, so that we have a core portfolio to maintain on the Cochrane Library.

We started by defining 8 specialties, and then by asking the authors of our reviews in each specialty to rank our existing reviews on how important they felt they were to clinical practice and to patients. We also asked each group to identify any gaps they could see or topics they felt had not been addressed.

We’re now looking for feedback on 6 of the areas. Do you agree with the rankings? Do you think the new title proposals are useful?

Click on the links in the list below to read the discussion documents and view the rankings for each specialty:

You can send feedback on any of the discussion documents to us via email:, or you can visit our website and fill in the online form in the right hand column. The deadline for receipt of comments is Friday 1 August.


New publications from the Oral Health Group in the Cochrane Library, 2013, Issue 2

200Issue 2 of the Cochrane Library for 2013 was released today, and features one new review and three new protocols from the Oral Health Group.

We now have a total of 200 published systematic reviews and protocols on the Library, congratulations to all of our authors, editors and referees on this fantastic achievement!

New review:
Dental extractions prior to radiotherapy to the jaws for reducing post-radiotherapy dental complications
by Shiyana Eliyas, Ahmed Al-Khayatt, Richard WJ Porter, Peter Briggs

This new review aimed to assess the effects of maintaining the patient’s natural dentition during radiotherapy in comparison to extracting teeth before radiotherapy in areas that are difficult to access by the patient and the dentist, should reduction in mouth opening occur after radiotherapy to the jaws. No clinical trials were identified, and there is no high quality evidence on this clinically important topic.

New protocol:
Interventions for the treatment of oral and oropharyngeal cancers: targeted therapy and immunotherapy
by Kelvin KW Chan, Anne-Marie Glenny, Susan Furness, Helen V Worthington

This review is the fourth in a series of Cochrane reviews looking at different treatment modalities for oral cavity and oropharyngeal cancers: surgical treatment, chemotherapy and radiotherapy. There is a great deal of current research into new therapies for cancer and many of these make the headlines in the news. However, there is a significant time lag between laboratory discoveries and the introduction of new treatments into clinical care. This review will evaluate the randomised controlled trials of targeted and immunological therapies for patients with oral cavity or oropharyngeal cancer.

New protocol:
Maxillary distraction osteogenesis versus orthognathic surgery for cleft lip and palate patients
by Dimitrios Kloukos, Piotr Fudalej, Patrick Sequeira-Byron, Christos Katsaros

The conventional orthognathic surgery for correction of maxillary retrusion/hypoplasia is a Le Fort I osteotomy. Distraction osteogenesis is the surgical process of correction of skeletal deformity utilizing bone lengthening by gradual mechanical distraction. This review will compare the effectiveness of the two methods in patients with orofacial clefts.

New protocol:
Professionally-applied chemically-induced whitening of teeth in adults
by Alonso Carrasco-Labra, Romina Brignardello-Petersen, Nicolás Yanine, Ignacio Araya, Gabriel Rada, R Graham Chadwick

Professionally-applied bleaching treatments have been used for a long time. Despite all of the information available, it is difficult for clinicians to determine which is the most effective treatment for tooth discolouration and the level of potential harms of these treatments. This review aims to assess the evidence about the beneficial and adverse effects of in-office, professionally-applied chemically-induced whitening of teeth in adult patients. It will complement another Cochrane systematic review of the evidence for the use of home-based treatment methods.