Updated systematic reviews from the Oral Health Group

799px-Medication_amoxycillin_capsule

c. Malcolm Koo under the Creative Commons Share-Alike License

Issue 7, 2013 of the Cochrane Library has been published, and features two new updates from the Cochrane Oral Health Group. Follow the links to read more!

New update: Interventions for replacing missing teeth: antibiotics at dental implant placement to prevent complications
By Marco Esposito, Maria Gabriella Grusovin and Helen V Worthington

This updated review looks at whether antibiotics should be given prior to dental implants to prevent infections which can threaten implant stability. Six randomized controlled trials were included, with 1,162 participants. All six of these trials compared the use of antibiotics to prevent infection (failures and complications) with no treatment or treatment with a placebo . The antibiotic used in all the trials was amoxicillin; doses and timing of doses varied, although most used a single dose taken just before the implant was placed. One of the trials, with 100 participants, also looked at different doses of amoxicillin taken at different times. It appears that the oral administration of two grams of amoxicillin one hour before placement of dental implants is effective in reducing implant failures. More specifically, giving antibiotics to 25 people will avoid one person experiencing early implant losses. It is still unclear whether postoperative antibiotics are beneficial, or which antibiotics work best.

New update: Fluoride varnishes for preventing dental caries in children and adolescents
by Valeria CC Marinho, Helen V Worthington, Tanya Walsh and Jan E Clarkson

This is an update of a review which looks at whether fluoride varnish is effective in preventing tooth decay in children. 22 randomized controlled trials were included, with a total of 12,455 participants. 13 of the trials looked at older children who have permanent (adult) teeth, and fluoride varnish was found to reduce decayed or missing teeth by 43%. Children who still have their baby or milk teeth were covered in 10 of the trials. For this group of children, fluoride varnish reduced decayed or missing teeth by 37%. The evidence produced has been found to be of moderate quality due to issues with trial designs.

Other highlights of the Cochrane Library, Issue 7 include: